I-Cephalomannine: Izinzuzo zokulwa nomdlavuza kanye nezempilo zama-alkaloid emvelo

I-Cephalomannine iwuhlobo lwe-alkaloid ekhishwe ku-genusCephalomannine.Inezinto eziningi eziphilayo, ezihlanganisa ukulwa nesimila, ukulwa nokuvuvukala kanye ne-anti-plasmodium.Emkhakheni wezokwelapha, i-trichinine isetshenziswa kakhulu ekwelapheni i-acute myeloid leukemia,i-acute promyelocytic i-leukemia, i-acute monocytic leukemia, njll.,futhi ihlanganiswe neminye imithi yokwelapha ngamakhemikhali ukuze kuthuthukiswe umphumela wokwelapha.Ngaphezu kwalokho, iphinde isetshenziswe ekulungiseleleni izidakamizwa ezivimbela ukuzivikela komzimba, ezidlala indima ebalulekile ekuthuthukiseni ukungatheleleki komzimba kanye nokuthuthukisa ukumelana. ye-cephalomanine izochazwa ngokuningiliziwe ngezansi, okuhlanganisa nomsebenzi wayo webhayoloji ekulweni nesimila, ukulwa ne-HIV, ukwehlisa i-cholesterol, kanye nokusebenza kwayo emkhakheni wezokwelapha.

I-Cephalomannineiwuhlobo lwe-alkaloid yemvelo enokwakheka kwamangqamuzana ayinkimbinkimbi, futhi iqukethe amaqembu amaningi asebenzayo, ayinikeza imisebenzi eminingi yomzimba.Ngokwe-anti-tumor, isithako esisebenzayo se-cephalomanine singasebenza kumaseli omdlavuza, ivimbele ukukhula nokusabalala kwawo, kuyilapho Cishe awukho umphumela kumangqamuzana avamile.Ngaphezu kwalokho, iphinde ibe nomthelela wokulwa ne-HIV, engasiza ekuvimbeleni ukuphindaphinda kwegciwane futhi ibambezele ukukhula kwesifo. isifo sinomphumela othile.

Emkhakheni wezokwelapha, i-cephalomanine isetshenziswa kabanzi ekulungiseleleni izidakamizwa ezikhethekile zokwelapha umdlavuza, i-leukemia nezinye izifo.Le mithi iyakwazi ukusizakala ngomsebenzi we-cephalomanine we-antitumor futhi ibe nomphumela omuhle wokwelapha emakhazeni amaningi avamile. .Ngaphezu kwalokho, i-cephalomanine iphinde isetshenziswe ekulungiseleleni izidakamizwa ezivimbela ukuzivikela komzimba, ezidlala indima ebalulekile ekuthuthukiseni ukuvikeleka komzimba womuntu kanye nokuthuthukisa ukumelana.

Ngamafuphi, njenge-alkaloid yemvelo,i-cephalomaniniinezinhlobonhlobo zemisebenzi yomzimba, okuhlanganisa ukulwa nesimila, ukulwa ne-HIV, i-cholesterol nokunye.Isetshenziswa kakhulu emkhakheni wezokwelapha nezimonyo futhi idlala indima ebalulekile empilweni yomuntu.Njengomkhiqizi ochwepheshe we-cephalomanine, sizoqhubeka nokuzinikela ekwenzeni ngcono izinga lomkhiqizo kanye nokuthuthukisa izinhlobo ezintsha ukuze sihlangabezane nesidingo esiqhubekayo semakethe.

Qaphela:Izinzuzo ezingaba khona kanye nezicelo ezivezwe kulesi sihloko zithathwe ezincwadini ezishicilelwe.

I-Yunnan Hande Biotechnology Co., LTD., njengomkhiqizi wezinto ezingavuthiwe ochwepheshei-cephalomanini, sizibophezele ekukhipheni nasekucwengisiseni ama-alkaloid ezitshalweni zemvelo i-Trichinine ukuze sinikeze ngemikhiqizo yekhwalithi ephezulu yenkundla yezemithi yomhlaba wonke.