I-Docetaxel: Umuthi Omusha Wokwelapha Ama-Cancer Amaningi Ngokuphazamisa Ama-Microtubules

I-Docetaxel umuthi osetshenziswa kakhulu ekwelapheni imidlavuza ehlukahlukene, esebenza ngokuphazamisa izakhiwo ze-microtubule kumaseli omdlavuza.Lesi sici senza i-docetaxel ibe isikhali esinamandla ekwelapheni kwesimila, ikakhulukazi ezimeni lapho ezinye izindlela zokwelapha zingasebenzi.

I.Indlela Yesenzo: Ukuphazamisa Ama-Microtubules Kumangqamuzana Omdlavuza

I-Docetaxelingeyesigaba se-taxane sama-chemotherapeutic agents, asebenza ngokuthinta izakhiwo ze-microtubule kumaseli, ngaleyo ndlela athinte ukuhlukana kwamangqamuzana.Ama-Microtubules ayizakhiwo ezibalulekile ngaphakathi kwamangqamuzana adlala indima ebalulekile ekuhlukaneni kwamangqamuzana, asiza ingqamuzana ukuba lihlukane libe amaseli amasha amabili.I-Docetaxel iyaphazamisa umsebenzi ojwayelekile walawa ma-microtubules, angavimbela noma abambezele ukukhula nokusabalala kwamangqamuzana omdlavuza.

II.Ukwelapha Imidladla eminingi

Umdlavuza Webele: I-Docetaxel idlala indima ebalulekile ekwelapheni umdlavuza webele, ikakhulukazi ezimeni lapho umdlavuza ususuthele kwezinye izingosi (ezigabeni ezithuthukisiwe) futhi ezinye izindlela zokwelapha zehlulekile ukunikeza imiphumela egculisayo. Ingasiza ukulawula ukuqhubeka komdlavuza webele.

I-Non-Small Cell Lung Cancer(NSCLC):I-NSCLC ingenye yezinhlobo ezivame kakhulu zomdlavuza wamaphaphu, futhi i-docetaxel ivamise ukusetshenziswa ngokuhlangana neminye imithi yokwelapha ngamakhemikhali ukwelapha izimo ezisezigabeni ezithuthukile noma lapho umdlavuza ususabalele kwezinye izingosi. ukwelashwa okuhlangene kungasiza ekubambezeleni ukukhula kwezimila.

I-Prostate Cancer: I-Docetaxel ivame ukusetshenziswa ekwelapheni umdlavuza wendlala yesinye, ikakhulukazi ezimeni lapho umdlavuza usudlulele ezigabeni ezithuthukile noma ezinye izindlela zokwelapha seziphelile. Ukuhlanganiswa kwayo nezinye izidakamizwa kungathuthukisa amathuba okwelashwa ngempumelelo.

Umdlavuza Wesisu (Umdlavuza Wesisu):I-Docetaxelisetshenziswa futhi ekwelapheni umdlavuza wesisu, ikakhulukazi ezinhlotsheni ezithile ezithile zomdlavuza wesisu.Ngokuvamile ihlanganiswa neminye imithi ukunikeza ukwelashwa okuphelele.

Ngokufigqiwe,i-docetaxel,isidakamizwa se-chemotherapy esivimbela ukuhlukana kwamangqamuzana ngokuphazamisa izakhiwo ze-microtubule kumangqamuzana omdlavuza, sibonise ukusebenza kahle okuphawulekayo ekwelapheni izinhlobo eziningi zomdlavuza. ukugadwa kochwepheshe bezokwelapha ukuze kuqinisekiswe umphumela omuhle wokwelapha nokuphepha kwesiguli.

Qaphela: Ukusebenza okunamandla nezinhlelo zokusebenza ezishiwo kulesi sihloko kuthathwe ezincwadini ezishicilelwe esidlangalaleni.

Ukufundwa Okunwetshiwe:I-Yunnan Hande Biotech Co.,Ltd.igxile ekukhiqizweni kwezinto zokusetshenziswa ze-docetaxel iminyaka engaphezu kwengu-20, futhi ukuphela komkhiqizi ozimele wezinto zokusetshenziswa zomuthi we-anticancer we-docetaxel ovunywe izikhungo ezilawulayo ezifana ne-US FDA, I-European EDQM, i-Australian TGA, i-Chinese CFDA, i-India, ne-Japan.