Izimpawu ze-albumin-bound paclitaxel

I-Paclitaxel iyisidakamizwa esisha se-anti microtubule, esisetshenziswa kabanzi ekwelapheni umdlavuza wesibeletho, umdlavuza webele, umdlavuza wamaphaphu, izimila zekhanda nentamo, umdlavuza womminzo, umdlavuza wesisu kanye ne-sarcoma yezicubu ezithambile. ngokuhlolwa okuqhubekayo kwentela kanye nokwenza ngcono okuqhubekayo kobuchwepheshe bokulungiselela.Ake sibheke izici ze-Albumin-bound paclitaxel.

I-albumin-bound paclitaxel:ama-nanoparticles enziwe nge-paclitaxel kanye ne-albumin ye-serum yabantu ngobuchwepheshe bokudlidliza obunomfutho ophezulu, i-albumin eyodwa ye-albumin nama-molecule ayisikhombisa e-paclitaxel ahlanganisiwe, kanye nendima ye-albumin receptor Gp60 kulwelwesi lweseli kanye ne-cysteine ​​​​inothile ye-acidic secretory albumen I-SPARC)kuzicubu zesimila isetshenziselwa ukukhuthaza umuthi ukuthi ungene kumaseli wesimila futhi wandise umphumela we-chemotherapy.

1, Ezokuphepha

I-albumin-bound paclitaxel:akudingeki uwoyela we-cosolvent polyoxyethyl castor, ongakhuphula ngokuphephile umthamo we-paclitaxel, afinyeze isikhathi sokumnika, futhi akukho ukwelashwa kusengaphambili okudingekayo.

2. Ukwelashwa ngaphambi kwesikhathi

I-albumin-bound paclitaxel ayidingi ukwelashwa kusengaphambili ukuze kuvinjelwe ukungezwani komzimba ngaphambi kokuphathwa.

3. Ukusabela okubi

I-Albumin-bound paclitaxel kanye ne-paclitaxel liposomes:Ngenxa yokuthuthukiswa kobuchwepheshe bokulungiselela, asikho isidingo sokwengeza izinto ezisizayo ezifana nowoyela we-polyoxyethyl castor, i-polysorbate 80, i-ethanol ephelele, njll., futhi ukuphepha kwezidakamizwa kuye kwathuthukiswa kakhulu.

4. Izinkomba

I-Albumin-bound paclitaxel:izincwadi ezifanele zibika ukuthi umuthi wayo owodwa kanye nenhlanganisela yomuthi iyindlela yokwelapha yomdlavuza webele webele oqhubeka ngokushesha noma owehlulekayo ekwelashweni kwemigqa eminingi.Iphinde ikhombise ukusebenza kahle okuthile kwe-paclitaxel kanye nomdlavuza webele ongemuhle kathathu oseke waba nawo. ngaphambilini belashwe nge-paclitaxel, futhi imiphumela emibi iyabekezeleleka.

Qaphela: Ukusebenza okunamandla nezinhlelo zokusebenza ezethulwe kulesi sihloko konke kuvela ezincwadini ezishicilelwe.

I-Yunnan Hande Biotechnology Co., Ltd ibisebenza ngokukhethekile ekukhiqizenipaclitaxel APIiminyaka engaphezu kwengu-20, futhi ingomunye wabakhiqizi abazimele bezwe be-paclitaxel API, umuthi olwa nomdlavuza osuselwe esitshalweni, ogunyazwe yi-US FDA, European EDQM, Australian TGA, Chinese CFDA, India, Japan kanye nezinye izinhlaka ezilawula izwe. .I-Hande ayikwazi ukunikeza izinga eliphezulu kuphelapaclitaxel izinto zokusetshenziswa,kodwa futhi nezinsizakalo zokuthuthukisa ezobuchwepheshe ezihlobene ne-paclitaxel formulation.Ngolwazi olubanzi, sicela ukhululeke ukusithinta ku-18187887160.