I-Paclitaxel New Formulations

Siyazi ukuthi i-Paclitaxel ayincibiliki emanzini, ngakho-ke i-Paclitaxel Injection yendabuko isebenzisa uwoyela we-castor ukuncibilikisa i-Paclitaxel, okuletha izinkinga ezimbalwa:

1.Izidakamizwa aziqondiswe kumathumba.Inani elikhulu lezidakamizwa lithinte umzimba wonke weziguli.Zonke izitho nezitho zomzimba zihlushwa ukulimala okunobuthi.Imiphumela engemihle yokwelashwa ngamakhemikhali ngezidakamizwa inamandla uma kuqhathaniswa;

2.Ngenxa yobuthi nemiphumela engemihle emzimbeni wonke, umthamo wezidakamizwa unomkhawulo, okuholela ekutheni ezinye iziguli zingasasebenzi ngemva kwesikhathi sokwelashwa futhi zilahlekelwe uhlelo lokwelapha olulandelanayo;

I-3.Amafutha e-Castor kulula ukubangela ukungezwani komzimba, ngakho-ke ngaphambi kwe-chemo ngayinye, isiguli sidinga ukwelashwa ngemithi ehlukahlukene ukuvimbela ukungezwani komzimba.

As I-Paclitaxelkusewumuthi osebenza kahle kakhulu, obanzi kakhulu emhlabeni, kuwumkhuba ongagwemeki wamafomu amasha nangcono wemithamo ukuthi athathe indawo yamafomu omthamo wokuqala.

Ngokohlaziyo lwedatha yomtholampilo kanye nenkambiso yokuthengisa ezimakethe, amafomu amabili emithamo angaba khona kanje angezansi:

1.I-Paclitaxel(I-Albumin-Bound for Umjovo)

2.I-Paclitaxel Polymeric Micelles Yomjovo

Lapha ake sibheke izinzuzo zalawa mafomu omthamo we-2.

Njengoba sibona etafuleni, lawa mafomu amabili emithamo amasha anezinzuzo ezisobala zomtholampilo, ngakho-ke asebenza kahle kakhulu ngemva kokumakethwa, aze athathe indawo ngokushesha imakethe yendabuko yePaclitaxel Injection.

I-Paclitaxel(I-Albumin-Bound for Umjovo)

Ngenxa yezinzuzo zayo zokusebenza kahle, ukusetshenziswa kalula nokuphepha okuphezulu, i-Paclitaxel(Albumin-Bound for Injection) isheshe yathatha indawo yemakethe yomjovo we-paclitaxel wendabuko, futhi yasetshenziswa kabanzi ezinkomba zesimila eziningi ngemuva kokufakwa ohlwini lomshwalense wezokwelapha lukazwelonke.

I-Albumin paclitaxel ekuqaleni yathuthukiswa njenge-Abraxane ye-BMS, futhi umthamo wayo wokuthengisa wawungu-0.9 billion USD ngo-2021.

Ngo-2021, ukuthengiswa kwe-Paclitaxel(Albumin-Bound for Injection) ekupheleni kwezikhungo zezokwelapha zomphakathi e-China kwafinyelela ku-4 billion yuan(572 Million USD), nokukhula okungaphezu kuka-10% engxenyeni yokuqala ka-2022.(inani labantu eChina: 1.4 billion)

I-Paclitaxel(I-Albumin-Bound Yomjovo) isiba ifomulation ethandwa kakhulu ye-Paclitaxel.Yamukelwa kabanzi iziguli, odokotela nohulumeni ngenxa yezinzuzo zayo kanye nenani elithengekayo.

I-Paclitaxel Polymeric Micelles Injection

I-Paclitaxel Polymeric Micelles Injection iwumuthi omusha othuthukisiwe owakhiwe ngokuzimela, ongeyona i-anda, futhi ongenambangi okwamanje.

Uma kuqhathaniswa ne-albumin paclitaxel, isebenza kangcono, ukuphepha, ukubekezelela izidakamizwa nezinye izinkomba, izinzuzo zokukhushulwa emtholampilo, nendawo enkulu yenzuzo.Ngakho-ke, isanda kugunyazwa ukuthi ithengiswe isigamu sonyaka, futhi ifinyelele inzuzo enkulu yezigidi ezingu-60 zamayuan. .

Kuze kube manje lona ukuphela komjovo we-Paclitaxel Polymeric Micelles ogunyaziwe emhlabeni wonke, kodwa izinkampani ezimbalwa zemithi ziphezu kwenqubo ye-R&D kanye nokuhlolwa kwemitholampilo emazweni ahlukene.

I-albumin nama-micelles abathwali abaphelele be-molecule encane izidakamizwa ezingancibiliki.Ngemva kwalokhoI-Paclitaxel,zingasetshenziswa futhi kuI-Docetaxel,I-Cabazitaxelkanye nezinye izidakamizwa ezingancibiliki.Inani lemakethe elethwa yilobu buchwepheshe likhulu kakhulu.

I-Hande Bio-Tech inikeza lonke iphakethe leukudluliswa kobuchwepheshekulawa mafomu emithamo emi-2, ukusekela iphrojekthi yakho ebalulekile ekutholeni imvume yokuhweba ngokushesha kakhulu kunabanye.

Xhumana nathi ukuze wazi kabanzi, ithuba kungaba elakho.