Iyini i-Semi-synthetic Paclitaxel?

Iyini i-Semi-synthetic Paclitaxel?I-Semi-synthetic Paclitaxelisidakamizwa esisetshenziselwa ukwelapha izinhlobo zomdlavuza.Iwuhlelo olwenziwe ngokwenziwa lwe-paclitaxel, olusetshenziswa kakhulu ekwelashweni komtholampilo ngenxa yomphumela wayo ovimbelayo kumaseli omdlavuza.

I-Paclitaxel iyinhlanganisela yemvelo ekhishwe ezihlahleni ze-Yunnan fir, ezinezakhiwo zokulwa nesimila.Nokho, ngenxa yomthombo olinganiselwe we-paclitaxel kanye nesakhiwo sayo esiyinkimbinkimbi, i-synthetic Semi-synthetic Paclitaxel isithathe indawo.I-Semisynthesis taxol itholakala ngokukhipha izinhlanganisela ezifanayo. kusuka kwezinye izitshalo, bese ngokusebenzisa ukusabela kwamakhemikhali nokuguqulwa.

Inqubo yokulungiselela i-Semi-synthetic Paclitaxel iyinkimbinkimbi kakhulu futhi idinga ukusabela kwezinyathelo eziningi. Okokuqala, izinhlanganisela ezifanayo zikhishwa ezitshalweni bese ziguqulwa zibe izandulela ze-paclitaxel ngokusabela kwamakhemikhali. Bese, ngochungechunge lokusabela nokwelashwa, isandulela iguqulelwe ku-Semi-synthetic Paclitaxel.Ekugcineni, i-Semi-synthetic Paclitaxel yahlanzwa futhi yacwebezelwa ukuze kutholwe izidakamizwa ezihlanzekile.

I-Semi-synthetic PaclitaxelIkhombise imiphumela emihle ekwelapheni umdlavuza ohlukahlukene.Ingavimba ukukhula nokubhebhetheka komdlavuza ngokuphazamisa inqubo yeMitosis yamangqamuzana esimila. Ngaphezu kwalokho, i-Semi-synthetic Paclitaxel ingathuthukisa ukusebenza kahle kwe-radiotherapy kanye nokwelashwa ngamakhemikhali, futhi yehlise ukuvuvukala. ukungakhululeki kweziguli.

Ekuphetheni,I-Semi-synthetic Paclitaxeliyisidakamizwa esilwa nomdlavuza esibaluleke kakhulu.Nakuba inqubo yaso yokuwulungiselela iyinkimbinkimbi, umphumela wayo wokwelapha ubaluleke kakhulu.Ngenqubekelaphambili eqhubekayo yesayensi nobuchwepheshe, kukholakala ukuthi i-Semi-synthetic Paclitaxel izodlala indima ebaluleke kakhulu ekwelashweni kwesikhathi esizayo. .