Buyini Ubudlelwano phakathi kwe-Paclitaxel ne-Paclitaxel ye-Injectable Suspension(Albumin Bound)?

Iyini i-paclitaxel,i-paclitaxel ye-suspension yomjovo kanye ne-albumin-bound paclitaxel?Iziphi izinto ezisetshenziswa kakhulu?Sizozichaza kafushane kulesi sihloko.

I-Paclitaxel:

I-metabolite yesibili engokwemvelo ehlukanisiwe futhi ehlanjululwe emagxolweni, amagatsha namaqabunga e-gymnospermous taxus chinensis ingakhuthaza i-microtubule polymerization futhi iqinise ama-microtubules a-polymerized.Amaseli avezwe ku-paclitaxel azoqoqa inani elikhulu lama-microtubules kumaseli.Ukuqoqwa kwalawa ma-microtubules kuyaphazamisa ngemisebenzi ehlukahlukene yamaseli, ikakhulukazi ukumisa ukuhlukana kwamaseli esigabeni se-mitotic, futhi ivimbe ukuhlukana kwamaseli okuvamile.

Inomphumela omuhle wokulwa nesimila futhi isetshenziselwa ukwelapha umdlavuza webele osezingeni eliphezulu, umdlavuza wamaphaphu, umdlavuza wesibeletho, umdlavuza wekhanda nentamo, umdlavuza wezicubu ezithambile kanye nomdlavuza wokugaya ukudla.

I-Paclitaxel(Taxol) i-anticancer API(I-Active Pharmaceutical Ingredient), engeke isetshenziswe abantu ngokuqondile.Idinga ukuhlinzekwa ezinkampanini ezingaphansi komfula noma izimboni zemithi ukuze ibe enye ye-API yemithi eqediwe.

Njengamanje, esetshenziswa kakhulu i-paclitaxel imijovo elwa nomdlavuza kanye nemishini yezokwelapha (okuhlanganisa ama-stents namabhaluni). Ngokuthuthuka okusheshayo kwe-biotechnology kanye nobuchwepheshe bezokwelapha, ukusetshenziswa kwe-paclitaxel nakho kuhlolwa njalo, kanye nezimo ezahlukene zeziguli nazo ithuthukiswa ngokuqhubekayo.Kholwa ukuthi esikhathini esizayo esiseduze, izophepheka futhi ibe lula ekwelapheni odokotela neziguli, futhi kuzoba nezinhlobonhlobo zemithi elwa nomdlavuza equkethe i-paclitaxel enamandla okulwa nomdlavuza.

I-Paclitaxel yokumiswa komjovo:

Umjovo oqukethe i-paclitaxel API.

I-Paclitaxel yomjovo ihlanganisa nomjovo we-polyoxyethylene castor kawoyela we-paclitaxel; umjovo we-Liposome paclitaxel; umjovo we-paclitaxel oboshwe nge-Albumin;I-Micellar paclitaxel namanye amafomu omthamo.

Isetshenziswa kakhulu kumdlavuza webele, umdlavuza wamaphaphu, umdlavuza wesibeletho nezinye izifo, futhi ingenye yemithi elwa nomdlavuza ephumelela kakhulu njengamanje.

I-Albumin Bound Paclitaxel:

Umjovo we-albumin oboshwe nge-paclitaxel uyilungiselelo elihlanganisa i-paclitaxel ne-albumin.Ungowe-paclitaxel yomjovo futhi ungomunye wemijovo ye-paclitaxel esetshenziswa kakhulu enokuphepha okuphezulu.

I-Albumin paclitaxel, eyokuqala ukungena emehlweni abantu Umjovo we-ABRAXANE(ABRAXANE For Injectable Suspension paclitaxel protein-bound particles for injectable suspension,albumin-bound) egunyazwe yi-FDA ngo-2005, esetshenziselwa ukwelapha umdlavuza webele we-metastatic. ukuhlakazeka kabusha cishe ku-130 nm, futhi akuqukethe izincibilikisi ezinobuthi.Umphumela wako wokuphepha kanye nomthelela wokwelapha uphakeme kakhulu kunalowo wamalungiselelo afanayo, futhi kudume kakhulu.Kuphinde kube ngesinye sezizathu eziyinhloko zocwaningo nokulingiswa. yamabhizinisi amakhulu emithi esikhathini esizayo.

Isebenza kakhulu ekwelapheni umdlavuza webele we-metastatic ongaphumeleli ekwelapheni ngamakhemikhali okuhlanganisiwe noma umdlavuza webele ophindela emuva phakathi nezinyanga eziyi-6 ngemva kokwelashwa ngamakhemikhali kwe-adjuvant.

I-Yunnan Hande Bio-Tech izibophezele ocwaningweni nasekuthuthukisweni nasekukhiqizenipaclitaxel,i-docetaxel,10-DAB semi-synthetic paclitaxel,futhii-cabazitaxel,futhi inocwaningo lwedatha oluningiliziwe mayelana nokungcola okuhlukahlukene okuqukethwe ku-paclitaxel.Ngaphezu kwalokho, i-Hande iphinde inikeze ngezinsizakalo zokudlulisa ubuchwepheshe ezihlobene ne-paclitaxel:imijovo ye-paclitaxel yendabuko;imijovo ye-albumin eboshwe nge-paclitaxel njll, siyakwamukela ukuthintana nathi ukuze ubuze!（Whatsapp/Wechat:+86 18187887160)