I-Ligustrazine Ligusticum chuanxiong ikhipha izinto zokusetshenziswa zemithi

Ulwazi Lomkhiqizo

I-Ligustrazine iyisakhi se-bioactive ekhishwe ku-Ligusticum chuanxiong, umuthi osetshenziswa kakhulu wamaShayina.Ingavimbela ukuhlangana kweplatelet, ithuthukise i-vasodilation, ikhuphule ukugeleza kwegazi lobuchopho futhi inomphumela we-neuroprotective.Umjovo we-Ligustrazine usetshenziswe kabanzi ekwelapheni isifo sohlangothi, isifo senhliziyo, isifo sikashukela kanye ne-osteoarthritis yamadolo e-China.I-Ligustrazine nayo iye yahlolwa njengokwelashwa komtholampilo kwezilonda zokucindezela, njenge-ejenti yokusiza iziguli ezine-lymphoma engeyona i-Hodgkin, futhi njengokwelashwa kwesifuba somoya esibangelwa yi-bronchial kanye nokungakwazi kahle kwe-vertebrobasilar.
1. Izici ze-Ligustrazine
I-Ligustrazine iyikristalu ye-acicular engenambala enephuzu lokuncibilika elingu-80-82 ° (ukuzimisela okuncanyana) kanye nephuzu elibilayo elingu-190 °.Inephunga elikhethekile, i-hygroscopicity kanye ne-sublimation elula.Incibilika kalula emanzini ashisayo ne-petroleum ether, i-chloroform kanye ne-dilute hydrochloric acid, inyibilika kancane ku-ether futhi ayincibiliki emanzini abandayo.
2, Umphumela we-Ligustrazine
1. Umphumela enhliziyweni
2. Khulisa ukugeleza kwenhliziyo
3. Khulisa imithambo yegazi eseceleni futhi wehlise umfutho wegazi
4. Thuthukisa ukujikeleza kobuchopho
5. Vimbela ukuhlanganiswa kweplatelet kanye ne-antithrombotic
6. Umphumela ohlelweni lokuchama
7. Thuthukisa i-microcirculation
8. Umphumela ohlelweni lokuphefumula
9. I-anti tumor
10. Thuthukisa ukusebenza komzimba
11. Ukulimala kwe-anti radiation kanye nokuzwela ngemisebe
3, Imodi yokukhiqiza ye-Ligustrazine
I-Dimethylpyrazine yalungiswa ngokufihlwa kwe-butanone nge-ethyl nitrite ukuze kukhiqizwe i-dimethylglyoxime, eyabe isincishiswa futhi yenziwa ngebhayisikili.Umkhiqizo we-cyclization reaction ugaywa ngesitimu, futhi i-distillate iyapholiswa, ifakwe ikristalu futhi ihlungwe ukuze kutholwe umkhiqizo ongahluziwe we-tetramethylpyrazine.I-recrystallization yamanzi kanye ne-activated carbon decolorization isetshenziswa ekucwengeni.Lapho ulungiselela i-hydrochloride yayo, isixazululo se-ethanol esiqukethe u-15% - 20% we-hydrogen chloride singengezwa nge-dropwise ku-acetone ukwenza usawoti.
4. Izinkambu zohlelo lwe-Ligustrazine
1. Imboni yezemithi: yokukhiqiza izidakamizwa.
2. Imboni yokudla: isetshenziswa njenge-ejenti yesinongo, isithuthukisi esinoshukela esiphuzweni esidakayo, i-ejenti yesinongo nesithasiselo sikagwayi.

Amapharamitha womkhiqizo

IPHROFAYELA YENKAMPANI
Igama Lomkhiqizo	i-ligustrazine
CAS	1124-11-4
I-Chemical Formula	I-C8H12N2
Birandi	Hfuthi
Mumenzi	YUnnan Hande Bio-Tech Co., Ltd.
Cukuphuma	Kunming,Chawu
Imisiwe	1993
BULWAZI LWE-ASIC
Omqondofana	I-Tetramethylpyrazine;2,3,5,6-tetramethylpyrazine;I-Pyrazine, i-tetramethyl-;
Isakhiwo
Isisindo	136.19400
HIkhodi ye-S	N/A
IkhwalithiSukucaciswa	Ukucaciswa Kwenkampani
Cizitifiketi	N/A
Isivivinyo	Kwenziwe ngokwezifiso ngokwezidingo zekhasimende
Ukubukeka	Ikristalu ye-acicular engenambala
Indlela Yokukhipha	i-rhizome ye-chuanxiong
Amandla Wonyaka	Kwenziwe ngokwezifiso ngokwezidingo zekhasimende
Iphakheji	Kwenziwe ngokwezifiso ngokwezidingo zekhasimende
Indlela Yokuhlola	N/A
Logistics	Okuningiezokuthuthas
PaymentTerms	T/T, D/P, D/A
Olapho	Yamukela ukuhlolwa kwamakhasimende ngaso sonke isikhathi;Siza amaklayenti ngokubhaliswa kokulawula.

1.Yonke imikhiqizo ethengiswa yinkampani iyimpahla esetshenziswayo engaqediwe.Imikhiqizo iqondiswe kakhulu kubakhiqizi abaneziqu zokukhiqiza, futhi izinto ezingavuthiwe aziyona imikhiqizo yokugcina.
2.Impumelelo engaba khona kanye nezicelo ezihilelekile esingenisweni konke kuvela ezincwadini ezishicilelwe.Abantu ngabanye abancomi ukusetshenziswa okuqondile, futhi ukuthenga ngakunye kwenqatshwa.
3.Izithombe kanye nemininingwane yomkhiqizo kule webhusayithi ingeyereferensi kuphela, futhi umkhiqizo wangempela yiwo oyosebenza.