Njengomuthi ongase uvimbele i-COVID_19,i-cepharanthineiyisithako esiyinhloko esisebenzayo esikhishwe ku-Stephania, umuthi wendabuko wamaShayina.Umuthi welungelo lobunikazi wamaShayina usufakwe ohlwini e-China naphesheya iminyaka engaphezu kwengu-40.
Ngomhlaka-10 Meyi, 2022, ososayensi baseShayina bathola ukwelashwa kwe-covid_ 19 imithi emisha ethole amalungelo obunikazi okusungulwa kukazwelonke. Ukucaciswa kwelungelo lobunikazi kubonisa ukuthi i-10μM(micromol/L) cepharanthine ivimbela ukuphindaphinda kwe-coronavirus izikhathi ezingu-15393.
Ngokushesha nje lapho lolu lwazi luphuma, kwakujabulisa kakhulu ngaphambi kokuba i-COVID 19 ingaxazululeki ngempumelelo. Nakuba i-cepharanthine isesigabeni sokucwaninga nokuthuthukiswa kwezidakamizwa futhi ingakaze isetshenziswe ngokusemthethweni emisebenzini yomtholampilo, futhi kuyizindaba ezinhle kakhulu kubo. isimo samanje se-Covid 19. Ngaphezu kwalokho, ngokwemibiko yabezindaba, ezinye izazi zaseMelika ziye zashicilela amaphepha esayensi ngaphambilini futhi zaqinisekisa ukuthi idatha yocwaningo lwe-cepharanthine ingcono kune-paxlovid, egunyazwe ukuthi ifakwe ohlwini. ibhizinisi lemithi lixhumane ne-US FDA ukwenza ucwaningo lwesilingo somtholampilo ekwelapheni i-COVID-19 nge-Cepharanthine. Kwethenjwa ukuthi kuzoba nenqubekelaphambili engcono ku-R&D nasekusetshenzisweni komtholampilo kwalo muthi maduze nje.
I-Cepharanthine(CEP) iyi-alkaloid eyenzeka ngokwemvelo etholakala ku-Stephania cepharantha Hayata futhi ibonise ukuthi ine-anti-inflammatory eyingqayizivele, i-antioxidative, i-immunomodulating, i-antiparasitic, ne-antiviral properties.
Amandla ayo okwelapha njenge-ejenti elwa namagciwane awakaze abaluleke ukwedlula ekulweni ne-COVID-19 ebangelwa i-acute acute Respiratory Syndrome virus type 2(SARS-CoV-2) virus.
Phakathi kwabanikazi abambalwa bamalungelo obunikazi, sinamalungelo obunikazi ahlobene nawoI-Cepharanthine.
I-Yunnan Hande Bio-tech Co.,Ltd.ingumkhiqizi nomnikezeli onokuhlangenwe nakho okungu-28+ ekukhishweni okugxilile nokuhlukaniswa kwezitshalo.Sinelungelo lobunikazi indlela yokukhiphaI-Cepharanthinekusukela ngo-August 2011.Ilungelo lobunikazi lethu lichaza ngokuningiliziwe ukuthi i-stephanine ikhishwa kanjani.Uma udinga i-Cepharanthine mayelana nalokhu, ungangabazi, sicela usithinte ngokushesha.
Isikhathi sokuthumela: May-16-2022