I-Sophora flavescens ikhipha i-Sophoridine 98% yezinto zokusetshenziswa zezimonyo

Ulwazi Lomkhiqizo

I-Sophora flavescens ekhishwe yi-Sophora flavescens, isitshalo se-leguminous.Okuqukethwe kwe-oxymatrine, ingxenye eyinhloko ephumelelayo, kungaphezu kwama-98%.Inemisebenzi namakhono okususa ukushisa, ukomisa umswakama, ukubulala izinambuzane kanye ne-diuresis.Isetshenziselwa isifo sohudo esishisayo, indle enegazi, i-jaundice, ukuvala umchamo, i-leucorrhea ebomvu, ukuvuvukala kwe-Yin, ukulunywa yi-Yin, i-eczema, izilonda ezimanzi, i-pruritus yesikhumba, utwayi, uchoko, ukwelashwa kwangaphandle kwe-trichomonal vaginitis.
1. Izingxenye eziyinhloko
I-Sophora flavescens ekhishwe ikakhulukazi iqukethe ama-alkaloid ahlukahlukene nama-flavonoids.Ama-alkaloid ikakhulukazi i-matrine ne-Oxymatrine, kanye ne-dehydro matrine, i-d-sophoricine, isisekelo sebhontshisi esinukayo esingu-1, i-1-methylgenistein, isisekelo seqabunga le-indigo sasendle esi-1, isisekelo sezimpande esingu-1-sophora, njll. I-Flavonoids ihlanganisa i-matrine, i-hypomatrine, i-sophoroside , isodehydrated icariin nokunye.
2. Umsebenzi
1. Ukuvikelwa kwe-mucosa yesisu
Ukukhishwa kwe-Sophora flavescens kunomphumela osobala wokuvikela ekulimaleni kwe-gastric mucosal okubangelwa i-hydrochloric acid, i-ethanol ne-indomethacin.Ingxenye yayo eyinhloko yizinhlanganisela ze-flavanone.
2. Umphumela wokulwa nokuvuvukala
I-Matrine inomphumela osobala wokulwa nokuvuvukala ekuvuvukeni okukhulu kwe-exudative okubangelwa ama-ejenti ahlukahlukene okuvuvukala (uwoyela we-croton, i-glacial acetic acid, i-carrageenan kanye neqanda elimhlophe), elifana nele-hydrocortisone.Ucwaningo luye lwabonisa ukuthi lo mkhiqizo unezici zezidakamizwa ezingezona ukuvuvukala.Ngaphezu kwalokho, i-matrine inomphumela wokuzinza ku-membrane ye-erythrocyte, futhi izidakamizwa ezinomphumela wokuzinza ku-erythrocyte zivame ukuba nomphumela wokuzinza ku-lysosomal membrane, ukuze kuncishiswe ukukhululwa kwabaxhumanisi abavuthayo futhi kufezeke injongo yokulwa nokuvuvukala.
3. Umphumela we-Antitumor
I-Sophocarpine nayo inomsebenzi wokulwa nomdlavuza.I-Matrine, i-Oxymatrine, i-sophocarpine kanye nezisekelo zayo ezixubile u-a, B no-C ngezilinganiso ezihlukene zibe nemiphumela ehlukene yokuvimbela isimila esiqinile se-S180.I-Matrine inomphumela obalulekile wokuvimbela izinga lokukhiqiza ikholoni lamaseli e-peripheral multidirectional hematopoietic progenitor ku-chronic myeloid leukemia.I-Sophora flavescens decoction ingaheha kakhulu amaseli e-leukemia ukuthi ahluke abe ama-monocyte macrophages lapho isebenza kumaseli e-promyelocytic leukemia yomuntu ku-vitro.
4. Umphumela wokukhulisa i-leukocyte
I-Oxymatrine ingavimbela i-leukopenia kumagundane abangelwa i-MMC ne-cyclophosphamide.Umjovo we-intravenous noma we-intramuscular of total Oxymatrine kanye ne-Oxymatrine ungandisa kakhulu inani le-peripheral leukocyte yegazi onogwaja abavamile.Ngaphezu kwalokho, isikhathi somphumela obalulekile, isikhathi sokugcinwa kanye nenani eliphakeme kakhulu le-leukocyte count ye-oxymatrine konogwaja abavamile ngokuyisisekelo kuyafana phakathi nezinsuku eziyi-18 ngemva kokuphathwa, Umphumela wokuba mhlophe ungcono kunotshwala besibindi sikashaka.
5. Umphumela ohlelweni lwenhliziyo nemithambo yegazi
Umjovo we-intravenous we-matrine ne-Oxymatrine waphikisana kakhulu ne-arrhythmias ebangelwa i-aconitine ne-chloroform adrenaline kumagundane;Umjovo we-Intraperitoneal waphikisa kakhulu futhi i-chloroform yenza i-fibrillation ye-ventricular kumagundane, yandisa umthamo we-aconitine eyenga i-arrhythmia kumagundane, kanye ne-arrhythmia ephikisanayo eyenziwa yi-barium chloride kanye nokuxhunyaniswa komthambo we-coronary owehla ngaphambili kumagundane.
6. Umphumela we-Antiasthmatic kanye ne-expectorant
I-Matrine ibangelwa kakhulu yinjabulo β Receptors, ikakhulukazi isikhungo esijabulisayo β Receptor, ekhulula i-bronchospasm futhi ivimbele ukukhululwa kwamasosha omzimba kanye nezinto ezisebenza kancane.
7. Umphumela wokuzinzisa
I-Matrine ingavimbela ngokuphawulekayo ukuhamba ngokukhululekile kwamagundane;Ivimbele kakhulu ukusebenza kwamagundane;Umthamo ophezulu ungavimbela ukulwa nokuziphatha okunolaka kwamagundane anesizungu.
8. Umphumela we-Antifungal
I-Sophora flavescens decoction inomphumela ovimbelayo kusikhunta esivamile sesikhumba.
9. I-bacteriostasis
Ukukhishwa kwe-Sophora flavescens kungavimbela i-Staphylococcus, i-Pseudomonas aeruginosa kanye ne-Mycobacterium tuberculosis.
10. Umphumela ohlelweni lwezinzwa olumaphakathi
Lapho i-matrine ijova onogwaja, ukukhubazeka kwemizwa emaphakathi kwatholakala, i-spasm yenzeke ngesikhathi esifanayo, futhi ekugcineni ukuphefumula kwema futhi kwafa.Uma ijova eseleseleni, iqala ijabule, bese iyakhubazeka, futhi ukuphefumula kuba kancane futhi kungajwayelekile.Kamuva, kwenzeka i-spasm, okuholela ekuboshweni kokuphefumula nokufa.Ukuhlaselwa kwe-spasm cishe kubangelwa i-hyperreflexia yomgogodla.
11. Umphumela we-Antiarrhythmic
I-Sophora flavescens inomphumela omuhle wokuphikisa ku-arrhythmia ebangelwa i-aconitine, i-amine enozwela kanye nobuthi be-digitalis, futhi umphumela wayo ufana ncamashi ne-quinidine.Okusho ukuthi, ngokuthinta i-potassium ne-sodium conduction system ye-cardiomyocyte membrane, isikhathi sokuphikisa ngokuphelele se-myocardium siyandiswa futhi ukucindezeleka kuyancipha, ukuze kuvinjwe i-ectopic pacemaker futhi idlale indima ephikisana ne-arrhythmia.Isithako esisebenzayo ekuqaleni kwafakazelwa ukuthi siyingxenye ye-alkaloid.Ngenxa yokuthi i-Sophora flavescens ayinawo umthelela ekuvuthweni kwe-myocardial kanye nokushaya kwenhliziyo yexoxo ku-vivo namagundane, ayikukhulisi ukusetshenziswa kwe-oksijini ye-myocardial futhi ikhulise ukwehluleka kwenhliziyo nokushaqeka, okufanele ukunakwa kwenhliziyo ye-ischemic.
3. Inkambu yohlelo lokusebenza
1. Imboni yezemithi: isetshenziselwa uhudo olushisayo, indle enegazi, i-jaundice, i-dysuria, i-leucorrhea ebomvu, ukuvuvukala kwe-Yin nokulunywa yi-Yin, i-eczema, izilonda ezimanzi, ukulunywa kwesikhumba, utwayi, uchoko, ukwelashwa kwangaphandle kwe-trichomonal vaginitis.
2. Imboni yezimonyo: I-Sophora flavescens extract ine-whitening, anti-inflammatory, anti acne, antibacterial kanye neminye imiphumela.Isetshenziswe ebuhleni nasekunakekeleni isikhumba ekuqaleni kwamakhulu eminyaka edlule.Manje isiyintandokazi yezimonyo zokusetshenziswa kwezimonyo ezinkulu.

Amapharamitha womkhiqizo

1.Yonke imikhiqizo ethengiswa yinkampani iyimpahla esetshenziswayo engaqediwe.Imikhiqizo iqondiswe kakhulu kubakhiqizi abaneziqu zokukhiqiza, futhi izinto ezingavuthiwe aziyona imikhiqizo yokugcina.
2.Impumelelo engaba khona kanye nezicelo ezihilelekile esingenisweni konke kuvela ezincwadini ezishicilelwe.Abantu ngabanye abancomi ukusetshenziswa okuqondile, futhi ukuthenga ngakunye kwenqatshwa.
3.Izithombe kanye nemininingwane yomkhiqizo kule webhusayithi ingeyereferensi kuphela, futhi umkhiqizo wangempela yiwo oyosebenza.