Amasevisi okudlulisa ubuchwepheshe okwakhiwa kwe-albumin-conjugated paclitaxel

Incazelo emfushane:

I-Paclitaxel iyisidakamizwa esilwa nesimila esisetshenziswa kakhulu.Umjovo we-paclitaxel osetshenziswa njengamanje emtholampilo usebenzisa uwoyela we-polyoxyethylene castor njenge-solubilizer, kodwa izehlakalo zokusabela kabi ziphezulu ngesikhathi sokusetshenziswa emtholampilo, ngakho isiguli sidinga ukwelashwa okulwa nokungezwani komzimba ngaphambi kokuphathwa, okuletha ukuphazamiseka okuningi ezigulini nakodokotela.Ukuze kuqedwe ukusabela okungekuhle okubangelwa uwoyela we-polyoxyethyl castor,unqobe ubuthakathaka bamalungiselelo akhona,futhi andise ukuncibilika nokuzinza kwe-paclitaxel,i-Albumin-bound paclitaxel yaba khona.I-Hande Biotech inikeza Ubuchwepheshe izinsiza zokudlulisa ze-albumin-conjugated paclitaxel formulations.Ukuthola imininingwane eyengeziwe, sicela uthintane ku-inthanethi.

Thumela i-imeyili kithi

Imininingwane Yomkhiqizo

Omaka bomkhiqizo

Ulwazi Lomkhiqizo

Igama:I-albumin-conjugated paclitaxel

Isithako esisebenzayo:I-Paclitaxel

Izinto ezisizayo:i-albhamuin ye-serum yomuntu

Izinkomba

Kusebenza ekwelapheni umdlavuza webele we-metastatic ongaphumeleli ekwelapheni ngamakhemikhali okuhlanganisiwe noma umdlavuza webele ophindela emuva phakathi nezinyanga ezingu-6 ngemva kokwelashwa kwe-adjuvant chemotherapy.Ngaphandle uma kukhona ukungqubuzana komtholampilo, ukwelashwa ngamakhemikhali kwangaphambilini kufanele kuhlanganise nomuthi we-anthracycline anticancer; I-carboplatin ehlanganisiwe isetshenziselwa umugqa wokuqala. ukwelashwa komdlavuza wamaphaphu wamaphaphu osezingeni eliphezulu noma we-metastatic ongewona omncane ongakulungele ukuhlinzwa noma ukwelashwa nge-radiotherapy kubantu abadala;Inhlanganisela ye-gemcitabine yokwelashwa komugqa wokuqala womdlavuza we-pancreatic metastatic omdala;Umdlavuza we-pancreatic.Ngaphezu kwalokho, iyasebenza naku-melanoma ye-metastatic. kanye ne-platinum ezwelayo noma umdlavuza we-ovarian ongazweli weplatinamu.