I-Artesunate 99% CAS 88495-63-0 i-Artemisia annua extract

Ulwazi Lomkhiqizo

I-Artesunate yenziwe ngesakhi esisebenzayo i-artemisinin ekhishwe ku-Artemisia annua, eyingqayizivele e-China, ngokuhlanganiswa kwamakhemikhali.Isebenza kakhulu ezigabeni ezibomvu zezinambuzane zikamalaleveva.Iwukuphela kokuphuma okusebenzayo kwe-artemisinin okungenziwa amalungiselelo ancibilikayo emanzini njengamanje.Ingabulala i-Plasmodium esigabeni se-erythrocytic futhi izuze umphumela we-antimalarial.Inezici zomsebenzi ophezulu we-antimalarial, i-antipyretic esheshayo, isikhathi esifushane sokuguqulwa okungalungile kwe-Plasmodium, kanye nemiphumela emincane enobuthi nemiphumela engemihle.Kuyisinqumo sokuqala sokwelapha umalaleveva onzima.
1. Imvelaphi yezitshalo
I-Artesunate iyi-semisynthetic artesunate derivative.
2. Indlela yokwenza
Indlela yokusebenza ye-artesunate artemisinin.Iqala isebenza kulwelwesi lwe-vesicle yokudla, ulwelwesi olungaphezulu kanye ne-mitochondria yePlasmodium.Eyesibili i-nuclear membrane kanye ne-endoplasmic reticulum.Ngaphezu kwalokho, iphinde ibe nomthelela othile ku-chromatin ku-nucleus.Njengoba lo mkhiqizo uqala ukusebenza kulwelwesi lwebhamuza lokudla, ngaleyo ndlela uvimbe ukudla okunomsoco, isilokazane sikamalaleveva sibulawa indlala ngokushesha ama-amino acid, sakha ngokushesha ama-autophagic vesicles, futhi siphuma ngokuqhubekayo emzimbeni, silahlekelwa inani elikhulu le-cytoplasm bese siyafa.
3. Indima
1. Izidakamizwa ze-Antiparasite
I-Artesunate iyisidakamizwa esisetshenziswa kakhulu se-antiparasite.Iphuma ku-artesunate enesakhiwo se-sesquiterpene lactone, okuyi-artesunate encishisiwe.
2. Imiphumela engaba khona yokulwa nomdlavuza
I-Artesunate inomthelela omkhulu wokubulala kumaseli wesimila futhi akulula ukukhiqiza ukumelana nomuthi.Eminyakeni yamuva nje, izazi zasekhaya nakwamanye amazwe zithole ukuthi i-artesunate ingadlala indima yokulwa nesimila ngokuvimbela ukwanda kwamangqamuzana e-tumor, ibangele ukuhlukaniswa kwamaseli e-tumor kanye ne-apoptosis, ilawule ukudluliswa kwesignali yamangqamuzana, ivimbele i-angiogenesis yesimila, ivimbele ukuhlasela kwesimila kanye ne-metastasis, ikhuthaze i-anti. -imithi ye-chemotherapy yesimila kanye nokuhlehlisa ukumelana nemithi.
4. Inkambu yohlelo lokusebenza
1. Imboni yezemithi

Amapharamitha womkhiqizo

IPHROFAYELA YENKAMPANI
Igama Lomkhiqizo	I-Artesunate
CAS	88495-63-0
I-Chemical Formula	C19H28O8
Birandi	Hfuthi
Mumenzi	YUnnan Hande Bio-Tech Co., Ltd.
Cukuphuma	Kunming,Chawu
Imisiwe	1993
BULWAZI LWE-ASIC
Omqondofana	I-ARTENSUNATE;Butanedioicacid,1--[(3R,5aS,6R,8aS,9R,10S,12R,12aR)-decahydro-3,6,9-trimethyl-3,12-epoxy-12H-pyrano[4,3-j ]-1,2-benzodioxepin-10-yl]ester;Artesunate(3R,5aS,6R,8aS,9R,10S,12R,12aR) -Decahydro-3,6,9-trimethyl-3,12-epoxy-12H -pyrano(4,3-j)-Chemicalbook1,2-benzodioxepin-10-olhydrogensuccinate;ARTESUNATE;ArtesunateC19H28O8;Artemisininmonosuccinate;ArtesunicAcid;ButanedioicAcidMono(3R,5aS,6R,8a01-R3R,9R) ,6,9-trimethyl-3,12-epoxy-12H-pyrano[4,3-j]-1,2-benzodioxepin-10-yl]Ester
Isakhiwo
Isisindo	384.42
HIkhodi ye-S	N/A
IkhwalithiSukucaciswa	Ukucaciswa Kwenkampani
Cizitifiketi	N/A
Isivivinyo	Kwenziwe ngokwezifiso ngokwezidingo zekhasimende
Ukubukeka	Ikristalu elimhlophe
Indlela Yokukhipha	U-Artemisia annua Linn.
Amandla Wonyaka	Kwenziwe ngokwezifiso ngokwezidingo zekhasimende
Iphakheji	Kwenziwe ngokwezifiso ngokwezidingo zekhasimende
Indlela Yokuhlola	I-HPLC
Logistics	Okuningiezokuthuthas
PaymentTerms	T/T, D/P, D/A
Olapho	Yamukela ukuhlolwa kwamakhasimende ngaso sonke isikhathi;Siza amaklayenti ngokubhaliswa kokulawula.

1.Yonke imikhiqizo ethengiswa yinkampani iyimpahla esetshenziswayo engaqediwe.Imikhiqizo iqondiswe kakhulu kubakhiqizi abaneziqu zokukhiqiza, futhi izinto ezingavuthiwe aziyona imikhiqizo yokugcina.
2.Impumelelo engaba khona kanye nezicelo ezihilelekile esingenisweni konke kuvela ezincwadini ezishicilelwe.Abantu ngabanye abancomi ukusetshenziswa okuqondile, futhi ukuthenga ngakunye kwenqatshwa.
3.Izithombe kanye nemininingwane yomkhiqizo kule webhusayithi ingeyereferensi kuphela, futhi umkhiqizo wangempela yiwo oyosebenza.

Imboni yezandla:

I-Yunnan hande Biotechnology Co., Ltd., eyasungulwa ngo-Agasti 1993, iyibhizinisi lobuchwepheshe obuphezulu eligxile ocwaningweni nasekuthuthukisweni kwe-biotechnology.Ngemva kweminyaka yokuthuthuka, i-hande isungule uhlelo oluphelele lwekhwalithi, ilawula ikhwalithi yemikhiqizo ngokuvumelana namazinga aphezulu, futhi yandisa inani lokukhipha amandla okukhiqiza.Imikhiqizo yayo isiphasise isitifiketi semithetho neziqondiso zamazwe ngamazwe, futhi ibe umkhiqizi wezitshalo ezingavuthiwe okwenza wonke umuntu azizwe ekhululekile.