Isakhiwo samakhemikhali negama
Igama:I-Ferulic acid
Inombolo ye-CAS:1135-24-6
Inombolo ye-EINECS:208-679-7
Isisindo samangqamuzana:194.18g/mol
Ifomula ye-molecular:I-C10H1004
Isakhiwo samakhemikhali:
Izici zomkhiqizo:
1 Ukususa ama-radicals mahhala
I-Ferulic acid inomphumela onamandla wokulwa ne-antioxidant, ongaqeda ama-radicals angenawo umoya-mpilo, uvimbele ama-enzyme akhiqiza ama-radicals mahhala, ukhuthaze ukukhiqizwa kwama-enzyme aqeda ama-radicals mahhala, aqede ukulimala kwe-oxidative kulwelwesi lwamaseli kanye ne-DNA ebangelwa ama-radicals mahhala, futhi avikele umzimba kuwo. umonakalo omkhulu wamahhala.
2 Ukuba mhlophe
I-Ferulic acid ingavimbela ukusebenza kwe-B16V kuma-melanocytes, futhi ukusebenzisa isixazululo se-ferulic acid esingu-0.1-0.5% kunganciphisa inani lama-melanocyte lisuka ku-117±23/mm2 liye ku-39±7/mm2; ngasikhathi sinye, i-ferulic acid ingavimbela Umsebenzi we-tyrosinase.Isixazululo se-ferulic acid esine-5mmol/L singavimbela umsebenzi we-tyrosinase kufika ku-86%.Ngisho noma ukugcwala kwesisombululo se-ferulic acid kungu-0.5mmol/L kuphela, izinga lokuvinjelwa kwalo emsebenzini we-tyrosinase lingafinyelela cishe 35%.
3 Ukumelana nokulimala kwe-UV
I-Ferulic acid iqukethe ama-conjugated bond aphindwe kabili, amunca ngokuqinile imisebe ye-UV esukela ku-290 kuye ku-350nm. Ekuhlanganiseni okungu-0.7%, ingavimbela ngempumelelo ububomvu besikhumba obubangelwa i-UVB, ivimbele futhi inciphise ukulimala kwe-UV esikhumbeni; i-asidi isiza ukuvimbela ukulimala kwamangqamuzana okubangelwa imisebe ye-ultraviolet, ithuthukisa ikhono lesikhumba lokumelana nokuthwebula izithombe futhi ivimbele umdlavuza wesikhumba.
4 Ukulwa nokuvuvukala
I-Ferulic acid ine-anti-inflammatory and wide-spectrum anti-allergic effect, kanti izinga lokuvimbela i-IL-4 ekuhlanganiseni kwe-4umol/L lingu-18.2%.
5 Ukutholakala kwe-bioavailability
I-Ferulic acid inomphumela okhuthazayo wokumuncwa kwe-transdermal, ngokungena kahle kwesikhumba kanye ne-bioavailability ephezulu.
Izinkomba zomkhiqizo
Isicelo somkhiqizo
Umthamo ophakanyisiwe:0.1%~0.5%
★Anti ukuguga kanye anti imibimbi imikhiqizo
★Imikhiqizo yokuvikela ilanga
★Imikhiqizo emhlophe nokukhipha amabala
★Imikhiqizo yokulungisa imisipha ezwelayo nokuvuvukala
★Imikhiqizo yamehlo
Amathiphu okupheka
I-pH esebenzayo: 3.0-6.0.
I-Ferulic acid iyancibilika emanzini ashisayo, kodwa ingancipha kalula ngemva kokupholisa; Kunconywa ukwandisa ukusetshenziswa kwe-polyols ohlelweni futhi wengeze i-cosolvent ethoxydiethylene glycol. Futhi ukulungisa i-pH ibe cishe ku-5.0 kunenzuzo ekuzinzeni kwezinga lokushisa eliphansi, futhi imvelo ye-pH ephezulu kakhulu ingasheshisa kalula i-oxidation kanye nokushintsha umbala kwe-ferulic acid.
Imininingwane yokupakisha
1kg/isikhwama,25kg/umgqomo
Isitoreji
Gcina endaweni epholile(<25℃), eyomile, nemnyama, evalwe futhi igcinwe.Kufanele isetshenziswe ngokushesha ngangokunokwenzeka ngemva kokuvula uphawu;Ngaphansi kwezimo zokulondoloza ezinconyiwe, imikhiqizo engavulwa ineshalofu lezinyanga ezingama-24.
