Isakhiwo samakhemikhali negama:
Igama le-INCI:I-Troxerutin/Troxerutin
Isiteketiso:I-Vitamin P4, i-Trihydroxyethyl Rutin
Inombolo ye-CAS:7085-55-4
Isisindo samangqamuzana:742.7 g/mol
Ifomula ye-molecular:I-C33H42019
Izici zomkhiqizo
"I-Catalogue of Names of Used Cosmetic Raw Materials(Ushicilelo luka-2015)"ekhishwe yi-National Drug Administration ihlanganisa i-troxerutin kule khathalogi enenombolo ye-serial 05450.
1 Umsebenzi webhayoloji kuma-capillaries
I-Troxerutin ingavimbela ukuhlangana kwamangqamuzana abomvu egazi namaplatelet, ikhuphule ukumelana nemithambo yemithambo emincane, ivimbele ukwanda kokungena kwe-capillary futhi inciphise ukugeleza kwegazi okungavamile kwama-capillaries, ivimbele i-thrombosis, ithuthukise i-microcirculation, ikhuphule okuqukethwe komoyampilo egazini, ikhuthaze ukugeleza kwegazi. ukwakheka kwemithambo yegazi emisha ukuze kuthuthukiswe ukujikeleza kwamaketango asemaceleni, njll.Ngakho-ke, isetshenziswa kakhulu emtholampilo ukwelapha i-cerebral thrombosis, thrombophlebitis, kanye nokopha kwe-capillary.
2 Thatha ngempumelelo i-ultraviolet futhi umelane nokukhanya okuluhlaza okwesibhakabhaka
Imisebe ye-UV ingabangela ukulimala kwesikhumba, ukuguga kwesikhumba, nokuguga kwesikhumba, kanye nomthelela wokukhanya okuluhlaza okwesibhakabhaka (400nm~500nm) ekukhanyeni okubonakalayo esikhumbeni akunakushaywa indiva. Ukungena kokukhanya okuluhlaza esikhumbeni kunamandla kune-UVA, kufinyelela esikhumbeni. i-dermis, iphazamisa isigqi se-circadian sesikhumba, isheshisa ukuthwebula kwesikhumba futhi ibangele umbala wesikhumba. I-Troxerutin ingavimba ngempumelelo ukukhanya kwe-ultraviolet nokuluhlaza okwesibhakabhaka kusuka ku-380nm kuya ku-450nm, futhi ukugxila okusebenzayo kungaba ngaphansi kuka-0.025%.
3 Ukumelana nokulimala kwe-UV
(1)Ingavimbela i-UVB eyenziwe i-apoptosis yamangqamuzana e-HaCaT(ama-keratinocyte angafi womuntu), ivimbele ukudluliselwa kwendlela yokusayina ye-MAPK kanye nezici zokuloba i-AP-1(c-Fos kanye ne-c-Jun), futhi ngaleyo ndlela ibambe iqhaza ekumelaneni nokulimala kokukhanya;
(2)Inkulumo yama-miRNA ingalawulwa ukuze kuvikelwe ama-nHDF(fibroblasts)kucindezelo lwe-oxidative elenziwe yi-UV kanye nokulimala kwe-DNA.
4 I-Antioxidant
Ucwaningo lwangaphambili lubonise ukuthi i-troxerutin ingavimbela i-Radiation induced lipid peroxidation ku-subcellular organelle, ulwelwesi lwamaseli kanye nezicubu ezijwayelekile zamagundane esimila.
I-Troxerutin ngokumelene ne-hydroxyl radical kanye ne-ABTS.+Umphumela wokuqeda wama-radicals wamahhala uyafana nalowo we-VC, okungenzeka uhlobane namaqembu e-phenolic hydroxyl eringini enuka kamnandi.
5 Thuthukisa umsebenzi wokuvimbela isikhumba
I-Troxerutin ingakwazi ukulawula i-miR-181a ukuze isheshise ukuhlukaniswa kwama-keratinocyte, ihlanganise "isakhiwo sodonga lwezitini" esikhumbeni, ngaleyo ndlela ithuthukise umsebenzi wokuvimbela isikhumba. Izinga lenkulumo ye-mRNA ekhuphukayo yezimpawu zokuhlukanisa i-keratinocyte (njenge-keratin 1, i-keratin 10, amaprotheni esikhumba, kanye ne-filaggrin) kuqinisekisile ukuthi i-troxerutin ingakhuthaza ukuhlukaniswa kwe-keratinocyte.
Isicelo somkhiqizo
Umthamo onconyiwe ngu-0.1-3.0%.
★Anti imikhiqizo eluhlaza okwesibhakabhaka
★Imikhiqizo yokukhipha igazi elibomvu
★Anti imikhiqizo yokuguga
★I-Leg Cream
★Imikhiqizo yokuvikela ilanga
★Imikhiqizo yokususa imibuthano emnyama ngaphansi kwamehlo
★Imikhiqizo emhlophe
★Imikhiqizo yokulungisa
Ukwaziswa komkhiqizo
I-Troxerutin inyibilika kalula emanzini futhi izinzile ekukhanyeni nasekushiseni; Ingengezwa ngokuqondile ngemuva kokuthi uhlelo lungaphansi kuka-45 ℃.
Imininingwane yomkhiqizo
1kg/isikhwama,25kg/umgqomo
Isitoreji
Gcina endaweni epholile, eyomile, nemnyama, evalwe ukuze igcinwe, futhi kufanele isetshenziswe ngokushesha ngangokunokwenzeka ngemva kokuvulwa.Ngaphansi kwezimo ezinconyiwe zokugcina, imikhiqizo engavuliwe ineshalofu lezinyanga ezingu-24.
