Imboni ye-GMP ithengisa okuqukethwe okuphezulu nokuhlanzeka okuphezulu kwe-10-DAB Semi-synthetic Paclitaxel

Ulwazi Lomkhiqizo

Igama:10-DAT Semi-synthetic Paclitaxel

Inombolo ye-CAS:33069-62-4

Ifomula yekhemikhali:I-C47H51NO14

Imininingwane:99%-102%

Umbala:impushana emhlophe noma ecishe ibe mhlophe

Umthombo:I-Taxus yunnanensis, i-Taxus chinensis

Uhlobo:Ama-API

Imiphumela kanye nezinzuzo

1.Umphumela we-Anticancer:I-10-DAB semi-synthetic paclitaxel inomphumela onamandla wokulwa nomdlavuza, ongavimbela ngempumelelo ukukhula nokusabalala kwamaseli wesimila futhi yenze i-apoptosis yeseli yesimila.Uma iqhathaniswa ne-paclitaxel yemvelo, i-10-DAB semi-synthetic paclitaxel ine-anticancer ephakeme. umsebenzi kanye ne-spectrum ebanzi ye-anticancer.

2.Ukuphepha:10-DAB semi-synthetic paclitaxel ekuklanyweni nasenqubweni yokukhiqiza, kugxilwe ekuthuthukiseni ukuphepha nokubekezela komkhiqizo.Ngokulungisa kanye nokwenza kahle ukwakheka kwamakhemikhali e-paclitaxel yemvelo, izehlakalo zemiphumela emibi kanye nokusabela okubi kuye kwancishiswa.

3.Izakhiwo ze-Pharmacokinetic:I-10-DAB semi-synthetic paclitaxel inezinto ezingcono ze-pharmacokinetic, ukuze ikwazi ukumuncwa kangcono futhi isatshalaliswe emzimbeni, ngaleyo ndlela ithuthukise umphumela wokwelapha.

4.Ukusebenza:I-10-DAB semi-synthetic paclitaxel ingasetshenziswa ukwelapha izinhlobo ezihlukahlukene zomdlavuza, okuhlanganisa wamaphaphu, webele, wesibeletho, isisu, nokunye.Ukusebenza nokuphepha kwayo kuye kwaqinisekiswa kabanzi ngokomtholampilo.

Izinkonzo Zethu

1.Imikhiqizo:Nikeza ngezingcaphuno zezitshalo zekhwalithi ephezulu, ezihlanzeke kakhulu, izinto zokusetshenziswa zemithi, nezimaphakathi zemithi.

2.Izinsizakalo zobuchwepheshe:Izingcaphuno ezenziwe ngokwezifiso ezinemininingwane ekhethekile ngokuya ngezidingo zekhasimende.