Umkhiqizi weCabazitaxel wekhwalithi ephezulu weCabazitaxel

Ikhwalithi ephezulu ye-cabazitaxel yamandla Umkhiqizi we-Cabazitaxel Isithombe esifakiwe
  • Umkhiqizi weCabazitaxel wekhwalithi ephezulu weCabazitaxel

Incazelo emfushane:

I-Carbataxel iyikhemikhali esetshenziselwa ukwenza izidakamizwa ezilwa nomdlavuza.I-Carbataxel iyimpushana emhlophe noma emhlophe ecishe ingancibiliki emanzini, kodwa inyibilika ku-ethanol.Indlela yayo yokulwa nomdlavuza nezici ziyafana ne-docetaxel, futhi ingeyesigaba semithi elwa ne-microtubule.Ngokusebenzisa hlanganisa ne tubulin, ukhuthaze ukuhlangana yayo zibe microtubules, ngasikhathi sinye kungavimbela lezi uye wabutha microtubule disassembly, ukuthi ukuzinza microtubules, ngaleyo ndlela inhibite cell mitosis, kanye interphase cell function (interphasecellularfunctions).


Imininingwane Yomkhiqizo

Omaka bomkhiqizo

Ulwazi Lomkhiqizo

Igama:I-Cabazitaxel

Inombolo ye-CAS:183133-96-2

Ifomula yekhemikhali:I-C45H57NO14

Imininingwane:99%

Umbala:impushana emhlophe noma emhlophe

Umthombo:Ihlanganiswe kancane ne-10-DAB

Uhlobo:Ama-API

Indima nezinzuzo ze-cabataxel

1.umphumela wokulwa nomdlavuza: i-carbamazel inomphumela onamandla wokulwa nomdlavuza, inganqanda ngempumelelo ukukhula nokusabalala kwamaseli wesimila, yenze i-tumor cell apoptosis.Uma kuqhathaniswa ne-paclitaxel yemvelo, i-carbataxel inomsebenzi ophezulu wokulwa nomdlavuza kanye ne-spectrum ebanzi yokulwa nomdlavuza.

I-2.ukuphepha: I-Cabataxel ohlelweni lokuklama nokukhiqiza, gxila ekuthuthukiseni ukuphepha komkhiqizo nokubekezelelana.Ngokushintsha kanye nokwenza kahle ukwakheka kwamakhemikhali e-paclitaxel, izehlakalo zemiphumela emibi kanye nokusabela okubi kuye kwancishiswa.

Izici ze-3.pharmacokinetic: i-carbamazel inezici ezingcono ze-pharmacokinetic, ukuze ikwazi ukumuncwa kangcono futhi isatshalaliswe emzimbeni, ukuze kuthuthukiswe umphumela wokwelapha.

4.ukusebenza: i-carbataxel ingasetshenziswa ukwelapha izinhlobo ezihlukahlukene zomdlavuza, okuhlanganisa umdlavuza wamaphaphu, umdlavuza webele, umdlavuza wesibeletho, umdlavuza wesisu, njll. Ukusebenza nokuphepha kwayo kuye kwaqinisekiswa kabanzi ngokomtholampilo.

5.Ukusekelwa kwesayensi: I-Cabataxel isekelwe ocwaningweni lwakamuva lwesayensi nokuthuthukiswa kobuchwepheshe, ngokusekelwa okuthembekile kwesayensi.

Izinkonzo Zethu

1.Imikhiqizo:Nikeza ngezingcaphuno zezitshalo zekhwalithi ephezulu, ezihlanzeke kakhulu, izinto zokusetshenziswa zemithi, nezimaphakathi zemithi.

2.Izinsizakalo zobuchwepheshe:Izingcaphuno ezenziwe ngokwezifiso ezinemininingwane ekhethekile ngokuya ngezidingo zekhasimende.

Imboni yezandla

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